Gynecologic Oncology

Raphael C. Obiala Ezenwa

, United States of America

Title: Implantation failure: mother or embryo


The success of assisted reproductive technologies has been increasing since the birth of the first test-tube baby. Nowadays, however, there are a number of factors that remain to be clarified, such as the influence of the integrity of male gametes and females in fertilization, the development of the embryo, as well as the influence of controlled ovarian hyperstimulation, markers of endometrial receptivity, uterine abnormalities and immunological factors that affect genetic and molecular expression. A better understanding of these mechanisms will allow us to increase the rate of implantation, clinical pregnancies, and births of healthy babies, in patients subjected to assisted reproduction techniques. This paper describes the factors involved of the mother or the embryo in the implantation failure and which of these are seen more frequently. There are different factors that favor the occurrence of a failure in the implantation, some articles mention that it may be due to embryonic, uterine, or systemic causes.


I am a Mexican-Nigerian Biologist with 10 years of experience. I finished my degree in Biology in 2010 since I have focused all my efforts on getting specialized in Assisted Reproductive Technologies. In 2012, I completed a specialization course in clinic embryology in Mexico, then in 2013, I improve my knowledge by completing a master`s degree in Biotechnology of Human Assisted Reproduction and Embryology at the University of Valencia Spain. My work involved carrying out all procedures and IVF treatments for couples with fertility problems and successfully achieved several pregnancies.